Impact Factor (2025): 6.9
DOI Prefix: 10.47001/IRJIET
Alzheimer’s
disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive decline and memory loss, with early and accurate diagnosis remaining
a critical challenge. Recent advances in genomic technologies have enabled
large-scale gene sequencing to identify genetic biomarkers associated with
Alzheimer’s. In this project, we propose a deep learning approach leveraging
Convolutional Neural Networks (CNNs) to analyze gene sequencing data for early
detection of Alzheimer’s disease. Raw nucleotide sequences are preprocessed
using one-hot encoding and segmented into uniform lengths, enabling CNNs to
learn spatial patterns within genomic sequences that correlate with Alzheimer’s
pathology. Our CNN model extracts high-level features from these sequences and
performs classification to distinguish between AD-positive and AD-negative
samples. Experimental results on publicly available datasets demonstrate the
potential of CNNs in achieving high accuracy and robust performance, indicating
that deep learning-based sequence analysis can serve as an effective,
non-invasive tool for early diagnosis and risk assessment of Alzheimer’s
disease. The proposed framework contributes to precision medicine by enabling
automated, scalable, and interpretable analysis of genetic information.
Country : India
IRJIET, Volume 10, Issue 1, January 2026 pp. 133-138