International Research Journal of Innovations in Engineering and Technology - IRJIET International Open Access, Monthly, Peer Reviewed, Reputed Journal ISSN (online): 2581-3048

Impact Factor (2025): 6.9

DOI Prefix: 10.47001/IRJIET

Alkylresorcinols as an Indicator of Whole-Grain Intake and Its Relation to Colorectal Carcinoma

Shalaby S.I.Department of Complementary Medicine, Medical Division, National Research Centre, Dokki, EgyptMayssa E-RzkyDepartment of Endemic Medicine, Faculty of Medicine, Cairo University, Cairo, EgyptMofeed ShehabDepartment of Endemic Medicine, Faculty of Medicine, Cairo University, Cairo, EgyptDina SabryDepartment of Medical Biochemistry, Faculty of Medicine, Cairo University, Cairo, EgyptIhab K.Abdel-AzizDepartment of Endemic Medicine, Faculty of Medicine, Cairo University, Cairo, EgyptMohamed AbdAllahDepartment of Endemic Medicine, Faculty of Medicine, Cairo University, Cairo, EgyptOmar El ShabacyDepartment of Complementary Medicine, Medical Division, National Research Centre, Dokki, EgyptDevendra Kumar AwasthiDepartment of Chemistry, Sri JN MPG College, Lucknow, India

Vol 6 No 4 (2022): Volume 6, Issue 4, April 2022 | Pages: 39-43

International Research Journal of Innovations in Engineering and Technology

OPEN ACCESS | Research Article | Published Date: 06-05-2022

doi Logo doi.org/10.47001/IRJIET/2022.604006

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Abstract
BACKGROUND: Alkylresorcinols are phenolic lipids that exclusively present in the outer parts of wheat and rye grains. They have been proposed as specific dietary biomarkers of whole-grain wheat and rye intake. Dietary fibers protective role aganist colorectal cancer has been postulated several decades ago. AIM: To verify the relation of dietary fiber intake and incidence of colorectal cancer using plasma total Alkylresorcinols concentrations as an indicator of whole-grain intake. METHODS: 148 Subjects were enrolled and categorixed into two groups; Group (A): 62 patients with colorectal cancer and Group (B): 86 subjects with normal colonoscopy “control group”. Blood samples were withdrawn from the patients after overnight fasting for detection of Alkylresorcinols levels. RESULTS: Detection of the Alkylresorcinols levels; C17, C21 and Total Cs were significantly higher in the control group in comparison to colorectal cancer group, C19 levels showed no significant difference. CONCLUSION: People with high intake of fibers especially cereals probably have a lower risk of developing cancer colon.
Keywords

colorectal cancer, Alkylresorcinols, cereals, protective


Citation of this Article

Shalaby, S.I., Mayssa E-Rzky, Mofeed Shehab, Dina Sabry, Ihab K.Abdel-Aziz, Mohamed AbdAllah, Omar El Shabacy, Devendra Kumar Awasthi, “Alkylresorcinols as an Indicator of Whole-Grain Intake and Its Relation to Colorectal Carcinoma” Published in International Research Journal of Innovations in Engineering and Technology - IRJIET, Volume 6, Issue 4, pp 39-43, April 2022. Article DOI https://doi.org/10.47001/IRJIET/2022.604006

Licence Copyright (c) 2026 International Research Journal of Innovations in Engineering and Technology creative common licence This work is licensed under Creative common Attribution Non Commercial 4.0 Internation Licence
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