This study uses annual time series data on under five mortality rate (U5MR) for Turkey from 1960 to 2020 to predict future trends of U5MR over the period 2021 to 2030. Residuals and forecast evaluation criteria indicate that the applied ANN (12, 12, 1) model is stable in forecasting under five mortality rate. ANN model projections revealed that annual U5MR will continue to decline over the out of sample period. Therefore, we encourage the Turkish government to address all the factors that significantly affect the successful implementation of the maternal and child health program.