Phytochemical Screening, Determination of Some Chemical Compounds and Antimicrobial Activity of Cassia Occidentalis (Senna coffee) (Whole plant) Found in Shelleng Local Government Area, Adamawa State, Nigeria

Abstract

This study was carried out to determine the phytochemicals, some chemical compounds and anti-microbial activities of Cassia occidentalis Roots, leaf, and seed found in Shelleng Local Government Area Adamawa State, Nigeria. The phytochemicals were extracted and analyzed using High Performance Liquid Chromatography (HPLC), the patent minerals were determined using Atomic Absorption Spectroscopy (AAS) and Flame Emission Spectroscopy (FES). The patent vitamins and proximate composition were analyzed using the standard methods. The results of the phytochemical constituents revealed the, presences of alkaloids, flavonoids, saponins, terpenes and phenols with phenols having the highest concentration.  The result of the proximate analyses showed that the plant has rich and good nutritional values having high carbohydrate contents, fiber and protein. Total ash content, fats and moisture were present in good amount. The result of the Patent vitamins revealed the presences of vitamin A, C, B6, B12 and K in the plant, with high concentration of vitamins A and C recorded in leave and seed, however, vitamin K was not detected. The result obtained revealed that Cassia occidetalis plant is rich in minerals. The following minerals were present K, P, Ca, Zn, Mn and Mg, with K, P and Ca recorded the highest concentration in the leave, seed and root. Other minerals such as Zn, Na, Fe, Cu, Mg and Mn are present in good amount and contributed to the nutritional values of the plant. The zone of inhibition, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined. The antimicrobial screening indicated that all the extracts exhibited different activity against different microbes. However, the results of this study showed that the extract of Cassia occidentalis plant could be potent in inhibition of the studied microorganisms and also the plant has good secondary metabolites. More research effort should be directed onto this species, in order to further validate many claims on the species. Research to be conducted on Cassia occidentalis to ascertained the level of its toxicity.

Country : Nigeria

1 Alexander, Priscilla2 Titus, Anbomutuntya3 Hassan Wafi Garba

  1. Department of Pure and Applied Chemistry, Faculty of Science, Adamawa State University, PMB 25, Mubi, Adamawa State, Nigeria
  2. Primary Health Care Development Authority Shelleng, Adamawa state, Nigeria
  3. Department of Pure and Applied Chemistry, Faculty of Science, Adamawa State University, PMB 25, Mubi, Adamawa State, Nigeria

IRJIET, Volume 8, Issue 11, November 2024 pp. 251-259

doi.org/10.47001/IRJIET/2024.811032

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