This paper introduces a novel hybrid framework for Indian Sign Language (ISL) translation that performs real-time recognition of both static and dynamic gestures and generates multilingual outputs in both text and speech. Unlike existing systems that are limited to either static classification or single-language outputs, our approach integrates a fine-tuned ResNet50V2 model for static gesture classification (98.7% accuracy) and a YOLOv8m detector for dynamic word recognition (88.7% mAP@50). The system employs MediaPipe for efficient hand landmark extraction and incorporates frame-skipping and cooldown strategies to optimize real-time performance on CPU-based devices, achieving an average of 3.4 FPS without GPU acceleration. Recognized gestures are mapped to sequences, translated into eight Indian languages using Google Translate, and converted into synthesized speech using gTTS. Experimental results validate the system's robustness across gesture types and linguistic outputs. The proposed work is the first to offer a complete ISL-to-text-and-speech pipeline with integrated multi-language support,via a desktop User-interface. This makes it a scalable, low-cost assistive tool designed to enhance accessibility and communication for the hearing-impaired community in multilingual contexts.