ESTD Year: 2017 | Impact Factor: 6.9
DOI Prefix: 10.47001/IRJIET
Vol 10 No 8 (2026): Volume 10, Issue 8, August 2026 | Pages: 123-128
International Research Journal of Innovations in Engineering and Technology
OPEN ACCESS | Research Article | Published Date: 31-08-2026
Early detection of lung nodules from computed tomography images is important for supporting timely lung cancer diagnosis. The research work represents a novel Pre-activation residual convolutional neural network with long short-term memory for lung nodule detection using LIDC dataset respectively. The proposed approach combines pre-activation residual learning with convolutional feature extraction to improve information propagation and preserve important image characteristics across deeper network layers. An LSTM component is incorporated to learn dependencies among the extracted feature representations and provide additional contextual information for classification. The framework includes image pre-processing, normalization, augmentation, feature extraction, sequential feature learning, and nodule classification consistently. The proposed approach is designed to capture both detailed local characteristics and higher-level contextual patterns associated with pulmonary nodules respectively. The performance of the classification and prediction accuracy were measured the area under receiver operating characteristic curve. The proposed method aims to provide a reliable and efficient computer-aided approach for automated lung nodule detection and to improve the consistency of computed tomography image analysis respectively.
Lung nodule detection, pre-activation residual CNN, LSTM, deep learning, computed tomography, LIDC dataset, lung cancer, medical image analysis, computer-aided detection
G. Paul Suthan, & Dr. Aruchamy Rajini. (2026). A Novel Enhanced Pre-Activation Residual CNN Approach for Lung Nodule Detection Using LIDC Dataset. International Research Journal of Innovations in Engineering and Technology - IRJIET, 10(8), 123-128. Article DOI https://doi.org/10.47001/IRJIET/2026.108013
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D. Lydia et. al. “An Improved Convolution Neural Network and Modified Regularized K-Means-Based Automatic Lung Nodule Detection and Classification,” Journal of Digital Imaging, vol. 36, pp. 1431–1446, 2023, doi: 10.1007/s10278-023-00809.
R. H. Prasada Rao et.al. “Cnidaria Herd Optimized Fuzzy C-Means Clustering Enabled Deep Learning Model for Lung Nodule Detection,” Frontiers in Physiology, vol. 16, Art. no. 1511716, 2025, doi: 10.3389/fphys.2025.1511716.
S. Dodia et. al.“A Novel Artificial Intelligence-Based Lung Nodule Segmentation and Classification System on CT Scans,” Computer Vision and Image Processing (CVIP 2021), Springer, pp. 552–564, 2022.
S. Katase et al.“Development and performance evaluation of a deep learning lung nodule detection system,” BMC Medical Imaging, vol. 22, Art. no. 203, 2022. DOI:10.1186/s12880-022-00938-8.
S. Şehribanoğlu et. al. “Efficient pulmonary nodules classification using radiomics and different artificial intelligence strategies,” Insights into Imaging, vol. 14, 2023, Art. no. 105, doi: 10.1186/s13244-023-01441-6.
K. Jeevitha et. al. “Lung nodule detection in CT images using ACM based segmentation method,” Turkish Online Journal of Qualitative Inquiry, vol. 12, no. 5, pp. 2379–2385, 2021.
S. Lalitha et. al. “An automated lung cancer detection system based on machine learning algorithm,” Journal of Intelligent & Fuzzy Systems, vol. 40, no. 4, pp. 6355–6364, 2021, doi: 10.3233/JIFS-189476.
S. S. Nair et. al.“Lung cancer detection from CT images: Modified adaptive threshold segmentation with support vector machines and artificial neural network classifier,” Current Medical Imaging, 2023, doi: 10.2174/1573405620666230714110914.
A.Bhattacharjee et. al. “A hybrid approach of data visualization technique and random forest classifier for binary classification of lung CT images,” in Proc. SIPCOV, 2024, doi: 10.2991/978-94-6463-529-4_21.
V. Thamilarasi et. al. “Medical image analysis using machine learning techniques for nodule and non-nodule classification,” ICTACT Journal on Image and Video Processing, vol. 15, no. 3, pp. 3501–3508, 2025, doi: 10.21917/ijivp.2025.0496.
Z. UrRehman et. al. “Effective lung nodule detection using deep CNN with dual attention mechanisms,” Scientific Reports, vol. 14, Art. no. 3934, 2024, doi: 10.1038/s41598-024-51833.
M. Tan et. al. “Pulmonary nodule detection using hybrid two-stage 3D CNNs,” Medical Physics, vol. 47, no. 8, pp. 3376–3388, 2020, doi: 10.1002/mp.14161.
A.Naik et. al. “Lung nodule classification on computed tomography images using deep learning,” Wireless Personal Communications, vol. 116, pp. 655–690, 2021, doi: 10.1007/s11277-020-07732-1.
Y. Yang et. al. “Application of artificial intelligence medical imaging aided diagnosis system in the diagnosis of pulmonary nodules,” BMC Medical Informatics and Decision Making, 2025. DOI: 10.1186/s12911-025-03009-4.